We know that skincare is deeply personal, and once you find something your skin loves, you don’t want to give it up. We want you to let Phyla be that system. 

For best results, we recommend that you use the Phyla system on its own. However, if you have other must-have products in your regimen, we recommend you use Phyla at night. Remove all makeup and other products from your skin, and apply the Phortify serum (and Phluff moisturizer) as the last products before you go to bed. 

Not only will this reduce the ingredient burden on your skin, but it will give our probiotic the best chance to work hard all night to recalibrate your microbiome and keep those breakouts at bay!

Our products are intentionally formulated to be gentle on the skin, and this goes double when your body is already stressed out with other treatments. While we can’t always predict how a specific treatment will affect our product, we ensure that our skincare line will not affect your other health treatments. However, it is always encouraged to check with your doctor first.

We are proud to make 100% of our formulations in the San Francisco Bay Area, California, USA. Our proprietary ingredient is made in small batches and with exacting standards at our local manufacturing facility in Sonoma County.

The Phortify Serum contains our proprietary live probiotic, and just like yogurt or kombucha (or any live probiotic), it needs to be refrigerated when not in use. The Phortify Serum is designed to be used continuously for 2 months at room temperature and incorporated into a daily skincare regimen.

While some of our customers see quick acne relief with our system, we highly recommend using our products as part of your long-term skincare regimen. Acne is a chronic skin condition, and fixing it takes time. Remember that your relationship with your skin is for life, and you will reap the benefits of a healthy microbiome long after your acne is resolved.

Stick with us for at least two months, and you’ll understand why.

While in most cases we did not see the skin get worse or have any side effects (like redness or irritation), it is possible that your skin gets a bit worse initially due to the recalibration process of your skin microbiome. We recommend using the Phyla system twice daily (especially during the night) for at least 2 months to stabilize your microbiome and see your skin health improve for the long term!

Our products do not help with fungal acne. You would need to see a doctor or dermatologist to get treatment.

We have tested the integrity of the product up to 1 month at room temperature with no effect on the probiotic. As the product sits at room temperature when it approaches the end of 2 months, it does start to lose some of its integrity as it is alive. So a week or even 2 weeks on vacation is no problem!

We recommend a powder-based or mineral-based sunscreen like zinc oxide and to always apply sunscreen before sun exposure. We know that sunscreens with silicones would probably affect our phage, and just to be safe when using these types of sunscreens, we recommend that you use your sunscreen for daytime use and our serum for nighttime use.

Yes, these products are non-irritating and completely safe to use while pregnant. However, it is always encouraged to check with your doctor first.

The Phyla’s system is designed to be used immediately upon receipt, and completely within 2 months, while incorporated into a daily skincare regimen. The Phortify Serum does contain a live probiotic, and we would encourage this to be refrigerated rather than storing at room temperature (we store it refrigerated before shipping to you)!

The Phortify Serum may also feel more soothing when applied with a light chill to it – kind of like a frosted glass. Ahhh!

Other probiotic skincare brands mostly sell dead, ground-up yogurt bacteria (look for ‘lysate’, ‘ferment’, or ‘extract’ in the probiotic ingredient label). And few skin products contain live bacteria, but those are mostly derived from yogurt or dirt.

Our probiotic is a living microorganism derived from healthy skin, and it specifically targets acne-causing bacteria. Thus we are the world’s first true skin probiotic – from the skin, for healthy skin.

We have observed that with severe or chronic acne (if you’ve had it for a long time with painful flare-ups), then the microbiome takes a while to recalibrate.

This might mean that you don’t see the rapid results that are generally seen with our system.

In this case, it’s best to use the entire Phyla system regularly (day and night) for at least 2-3 months and avoiding makeup or other products that might kill our probiotic.

You might even see your acne get slightly worse before it gets better; but we promise that you won’t experience the dryness, redness or irritation that you’d find with other harsh acne products!

This is possible. With any new skin care treatment, the bacteria on your skin need to re-adapt to its new regimen and rather than call it a purge, we call it a re-calibration of the microbiome.

Since everyone’s skin microbiome is different, no two microbiomes will react in the same way to this recalibration. That’s why we recommend you try the Phyla system for at least 2 months and minimize the use of other products to see the best results.

We offer a courteous 60-day success guarantee if you don’t see results after using the products for 2 months.

Contact your doctor right away if you experience an allergic reaction. Additionally, please email as soon as possible, and we will work with you to resolve the situation quickly.

While we follow all applicable FDA guidelines, we are not an FDA approved drug. If we were, you’d need a prescription!


No, unfortunately, our products are not formulated with sunscreen. We strongly recommend you use sunscreen during the daytime to preserve your skin. However, most sunscreens we have tested also kill our probiotic. Don’t worry, we are hard at work to develop a microbiome-friendly sunscreen that is compatible with our probiotic! In the meantime, we recommend adding the serum at night, when you won’t need sunscreen and, the probiotic can work hard while you sleep.

Yes, our products are 100% vegan and cruelty-free. We hold certifications from the Leaping Bunny Program and PETA’s Beauty Without Bunnies Program.

Further, our lab facilities are 100% animal component free.

There is only one strain of our proprietary probiotic, a bacteriophage, which specifically targets the bacteria associated with acne on your skin.

We wanted to keep the product simple in design and specifically for this acne care line we are only focused on rebalancing the skin to promote the growth of the non-acne causing bacteria.

We only add the probiotic to our Phortify Serum, while the other two products in our acne care line have been purpose-built and tested to support the growth of this probiotic and not be damaging to the skin microbiome.

Our technology is patent pending and is proprietary, but our blog shares a wealth of information about bacteriophages and help to spread the word on why we use this approach to chronic skin conditions caused by bacteria.

We have filed key patents for our proprietary probiotics (patent pending), and no other acne product contains this technology. We are also building on the results of our early testing and conducting a systematic trial to quantify these effects. We will reveal the trial data once it is ready. Further, we have several other products in advanced development that target other inflammatory skin problems like eczema.

All of our products are fragrance-free. Our Phortify Serum is unscented, and our Phluff Moisturizer is lightly scented with a natural citrus blossom oil.

Yes, all of our products are gluten-free/nut-free.

Our products contain NO sulfates, parabens, or phthalates.

A probiotic is defined as ‘live microorganisms which when administered in adequate amounts confer a health benefit on the host’.

Phages are a relatively new type of microorganism whose role in our health is being studied. Since phages don’t have a classification separate of their own, and fit the definition of a probiotic very well, we refer to it as a probiotic to avoid using obscure terms.

Some might point out that phages are viruses and therefore somewhere between living and non-living. However, the probiotics that we eat in pill form are not ‘alive’ in the pill since they are in a dormant state, and only get activated when they reach the gut.

Similarly, the phages are dormant in our serum, and activate once they encounter bacteria associated with acne.

We have developed a proprietary combination of the ingredients that you see in the serum that keeps the probiotic alive. 

We built the formulation from scratch, since live phages have never been used in a skin product before.

We tested each ingredient by itself and in combination with others, to make sure that it would keep our probiotic alive and potent.

After 4 years of research, we are proud to be have a shelf stable serum with live phages!


Your order might take a little longer to arrive due to COVID-19-related shipping delays, but we're still in business!

We currently ship to all 50 U.S. However, you may experience longer delivery times if you’re ordering from Hawaii and Alaska—thank you for being patient.

We’re doing our best, but it may take a few extra days to get to you.

In some (see: very few) cases, it may take 1 to 2 business days to digitally register your shipment status into the system. If your tracking number isn’t coming through or working at all, shoot us a note at with your order number, and we’ll get the problem sorted out for you ASAP.

Returns & Exchanges

Our mission is to get you on the path to clear skin for life, and we fully stand behind our products. That’s why we offer a 60-day success guarantee for all our products, starting from the date of delivery. Since it is important to let your skin settle into its new regimen, we request that you try it for at least 45 days; this gives you about 2 weeks to ask for a refund.

In order to request a refund, please contact us at to start the process. Your email must contain information about the product you purchased, the date of the purchase, and the email and name associated with that purchase.

We will send you a return label for your product, and you will receive your refund to the original mode of payment within 10 business days of receipt of your product.

For assistance, please email