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Science-Backed Solution for the Modern Age

With amazing advances in skin research and the microbiome, Phyla is focused on bringing the latest scientific breakthroughs to you. Our Ph.D. scientists from Johns Hopkins and UCSF, with 10 years of microbiome research experience, have discovered a unique probiotic that kills the acne bacteria and gets to the root cause of acne. The result: clear skin, without the skin damage.

What Causes Acne?

Acne has many causes: diet, hormones, genetics, and stress. But these are all secondary to the root cause of acne: the overgrowth of C. acnes, a bacteria that makes up 80-90% of all bacteria on your face [ref]. C. acnes love to feed on sebum, or the oil produced on your face. So acne can flare up with anything that affects the amount and type of sebum your skin produces, like how much you sweat (stress), what you eat (diet), your cycle (hormones), or your skin type (genetics).

The science used to tell us to control our sebum, to be less oily and wash our face to the point of dryness. But natural oils are essential to skin health, because they maintain the skin barrier, keep our skin supple and moist, and help it look more youthful. They’re literally food for your skin – and the acne bacteria. But remember, the problem is not the food – it’s the bacterial overgrowth. 

How Do We Treat Acne Now?

Take a look at the most popular acne products and you’ll notice their ingredients are all antibacterial in nature: benzoyl peroxide, antibiotics, even retinoids [Dematol (2002) 205(2), 153-8]. The problem with these ingredients is that they are indiscriminate killers: they destroy both the good and the bad bacteria. 

But what’s worse is what these harsh products do to your skin. Benzoyl peroxide is a form of bleach that produces dangerous free radicals, which damage the skin and activate aging pathways in skin cells. Retinoids accelerate the production of new skin cells, and result in your skin aging faster. Antibiotics cause antimicrobial resistance and an endless cycle of relapses. In short, you’re actually depleting this invisible shield that keeps your skin healthy and young.

The Future of Skincare

Imagine this: you go out to your garden, and you find a weed on your lawn. To get rid of the weed, do you pour gasoline all over your lawn to set it on fire? No, of course not! But you’re setting your microbiome on fire every day when you use harsh acne products.

Instead, you would just scoop out the weed, and replace it with a patch of grass. That’s exactly what Phyla’s approach does. Our revolutionary probiotic, a phage that targets C. acnes, kills only this acne bacteria without killing the good bacteria. As a result it rebalances your microbiome, increases diversity, and puts your skin on the path to long-term health. Don’t just take our word for it, check out the data from our clinical trial and our customers’ amazing results.

Clinical Trial

Recalibrating the microbiome for long-term skin health

Phyla kills only acne bacteria to boost microbiome diversity

The results from the study were astounding. As you can see above, the initial acne bacteria (red) is more than 3/4ths of all bacteria of the patient’s microbiome. When the phage reduces this level below 50%, other good bacteria (Corynebacteria and Staphylococci) start to thrive and increase the microbiome diversity. This is a key marker of long-term skin health, and our probiotic can help maintain a resilient microbiome and clear skin for the long term.

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Results reported after 8 weeks of use

Impressive Results

Before After
Before After

Founded By Scientists

Yug Varma, PhD

10+ years microbiome research
PhD in Microbiology, Johns Hopkins University

Maria Cho

15 years in pharma and commercial development
Masters in Biomedical chemistry

Phyla has partnered with UCSF since our inception through the QB3 biotech ecosystem and Center of Entrepreneurship. We continue to develop our technology with support from the leading dermatologists at the UCSF Department of Dermatology. 

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