To understand how our technology works, and why our approach is so revolutionary, let’s see how current acne products work. It’s important to note that the active ingredients in all acne products out there have an antibacterial effect – from over-the-counter products to strong prescription medication. Benzoyl peroxide and antibiotics simply kill all the bacteria they touch – they don’t discriminate between good and bad bacteria. This isn’t a good option, because other than being very harsh on your skin, they cause massive disruptions in your microbiome, which can leave you susceptible to skin infections. Also these harsh measures inevitably lead to recurring acne, since the bad strains tend to be more resilient and craftier than the good guys. Does any of this sound familiar to anyone who’s had to deal with le zits?
Retinoids are some of the most effective acne treatments we have, and it works by remodeling skin. It shrinks your pores and drastically cuts down on oil production, so it literally shrinks and starves the P. acnes out of its home. Of course, the heavy helping of side effects of retinoids comes with include extreme dryness and skin irritation, birth defects, liver damage, depression and suicide. For an acne drug. Oh, the things we do for clear skin.
And the fact is, since acne occurs in our youth when our skin is resilient, we are so eager to get rid of it that we don’t think twice before we bombard our fragile skin with all sorts of intense and harmful chemicals. Harsh substances like benzoyl peroxide and retinoids have been shown to activate pro-inflammatory pathways in our skin, which are also involved in aging. So while you’re desperately trying everything under the sun to push the acne off your skin, you don’t realize that in 20 years you’ll be wondering why your skin looks so much worse than it should, and what you could have possibly done differently.
Salicylic acid is a gentler, milder option than these, and kills P. acnes indirectly. Since P. acnes is anaerobic, it needs a clogged pore (aka whiteheads and blackheads) to keep the oxygen out. Salicylic acid is keratolytic, which means it breaks up these clogs and exfoliates the skin, exposing the P. acnes to oxygen and stopping it in its tracks. It also lowers sebum secretions, and robs the P. acnes of some of its food.
So it seems like all these products try to limit the growth of P. acnes indirectly, but they all do this in an indiscriminate way, killing both good and bad bacteria and being incredibly harsh on acne skin that needs to be treated with TLC. In an ideal world, we would simply get rid of the acne-causing bacteria without disturbing the good community of bacteria on our skin. Ideally, we could do so without being harsh on the skin, treating it with the care and consideration it deserves. Ideally, we could use this soothing treatment that gently reshapes your microbiome to health, well, forever. Without side effects. Without redness and irritation. Without irreparably damaging your skin and aging it prematurely.
The thing is, your microbiome is kind of like a beautiful garden that you tend and nurture with care. One day, you see a weed in your lawn. What do you do: douse the whole garden in gasoline and set it on fire, or just scoop up the weed and replace it with a patch of grass? Every time you use benzoyl peroxide and antibiotics on your skin, you’re basically setting your microbiome on fire. And up until now, you’ve had no option.
Here’s where we come in. We’ve discovered a brand new type of skin probiotic, called a bacteriophage (phage, for short). It eats bacteria, and it’s incredibly specific. It’s found in our skin all the time; in fact, it’s found far more frequently on healthy skin, and there’s a hypothesis that its natural occurrence correlated with the absence of acne could mean that it causes some people to never break out. Its specificity means that it will never kill or inhibit the growth of neighboring good bacteria, and because it is naturally found on healthy skin, we know (and have proven) that it is incredibly gentle on your skin and can be used every day without any harsh side effects. More excitingly, since it specifically kills P. acnes only, you can now eat all the spicy food you want, sweat as much as you like, and there will be no overgrowth from the bacteria feasting on your sebum. This means that over time, as the phage continually reshapes and recalibrates your microbiome towards health, you will see the long-term benefits of being acne-free – in the healthiest and gentlest way imaginable.
We’ve figured out a way to keep the phage alive in our formulation, which is no mean feat, and we are the world’s first true skin probiotic – no ground-up dead bacteria, no bacteria from yogurt or dirt. Our probiotic is a microorganism that lives selectively on healthy skin, and is probably the cause of healthy skin. Maybe some people are born with it, but we want to democratize this probiotic and make it accessible to everyone – so that we all can have the great-looking healthy skin we deserve.